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Curated Journal Articles on Mesothelioma

Category Archives: Environmental Asbestos Exposure

A comparison of asbestos fiber potency and elongate mineral particle (EMP) potency for mesothelioma in humans.

Toxicology and Applied Pharmacology 2018 August 2 [Link] Garabrant DH, Pastula ST Abstract We analyzed the mesothelioma mortality in cohorts of workers exposed to crocidolite, amosite, and chrysotile to estimate asbestos fiber potency for mesothelioma, using the method of Hodgson and Darnton (2000). We relied on the original 17 cohort studies in their analysis, along […]

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Epidemiological surveillance of mesothelioma mortality in Italy.

Cancer Epidemiology 2018 July 7 [Link] Fazzo L, Minelli G, De Santis M, Bruno C, Zona A, Conti S, Comba P Abstract BACKGROUND: Malignant mesothelioma (MM) is causally linked to asbestos exposure with an estimated etiological fraction of 80% or more. METHODS: Standardized rates of all mesothelioma (C45, ICD-10) and malignant pleural mesothelioma (C45.0, ICD-10) […]

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Measuring EMPs in the lung what can be measured in the lung: Asbestiform minerals and cleavage fragments.

Toxicology and Applied Pharmacology 2018 June 27 [Link] Roggli VL Abstract Asbestos mineral fibers have been associated with the development of a variety of diseases in humans and experimental animals, including asbestosis, lung cancer, and mesothelioma. Asbestos includes several mineral types divided into two mineral groups, serpentine and amphibole forms. Chrysotile is the serpentine mineral […]

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A review of the cohorts with environmental and occupational mineral fiber exposure.

Archives of environmental and occupational health 2018 April [Link] Metintas S, Ak G, Metintas M Abstract The aim of the study was to examine factors associated with Malignant Mesothelioma (MM) incidence rate of the groups with occupational asbestos and environmental asbestos or erionite exposure in rural area. In this ecological study, a total of 21 […]

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Environmental asbestos exposure and mesothelioma cases in Bari, Apulia region, southern Italy: a national interest site for land reclamation

Environmental Science Pollution Research International 2018 March 5 [Epub ahead of print] [Link] Vimercati L, Cavone D, Lovreglio P, De Maria L, Caputi A, Ferri GM, Serio G Abstract Asbestos is an environmental carcinogen, and asbestos-related diseases are a global-scale public health issue. We report three cases (one male and two females) of pleural malignant […]

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DNA methylation profiling of asbestos-treated MeT5A cell line reveals novel pathways implicated in asbestos response

Archives of Toxicology 2018 March [Epub ahead of print] [Link] Casalone E et. al. Abstract Occupational and environmental asbestos exposure is the main determinant of malignant pleural mesothelioma (MPM), however, the mechanisms by which its fibres contribute to cell toxicity and transformation are not completely clear. Aberrant DNA methylation is a common event in cancer […]

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Heterogeneous Contributing Factors in MPM Disease Development and Progression: Biological Advances and Clinical Implications

International Journal of Molecular Science 2018 January 13 [Link] Tolani B, Acevedo LA, Hoang NT, He B Abstract Malignant pleural mesothelioma (MPM) tumors are remarkably aggressive and most patients only survive for 5-12 months; irrespective of stage; after primary symptoms appear. Compounding matters is that MPM remains unresponsive to conventional standards of care; including radiation […]

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Chest physician-reported, work-related, long-latency respiratory disease in Great Britain

The European Respiratory Journal 2017 December [Link] Carder M, Darnton A, Gittins M, Stocks SJ, Ross D, Barber CM, Agius RM Abstract Much of the current burden of long-latency respiratory disease (LLRD) in Great Britain is attributed to historical asbestos exposure. However, continuing exposure to other agents, notably silica, also contributes to disease burden. The […]

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Biological responses to asbestos inhalation and pathogenesis of asbestos-related benign and malignant disease

Journal of Investigative Medicine 2018 January 6 [Epub ahead of print] [Link] Solbes E, Harper RW Abstract Asbestos comprises a group of fibrous minerals that are naturally occurring in the environment. Because of its natural properties, asbestos gained popularity for commercial applications in the late 19th century and was used throughout the majority of the […]

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The epidemiology of malignant mesothelioma in women: gender differences and modalities of asbestos exposure

Occupational and Environmental Medicine 2017 December 21 [Epub ahead of print] [Link] Marinaccio A, et. al. Abstract INTRODUCTION: The epidemiology of gender differences for mesothelioma incidence has been rarely discussed in national case lists. In Italy an epidemiological surveillance system (ReNaM) is working by the means of a national register. METHODS: Incident malignant mesothelioma (MM) […]

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