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Mesothelioma-Line

Curated Journal Articles on Mesothelioma

Category Archives: Causation

Articles dealing with the factors influencing the development of mesothelioma; occupational asbestos exposure is among the most common, but also genetic predisposition, smoking, and other contributing factors.

A comparison of asbestos fiber potency and elongate mineral particle (EMP) potency for mesothelioma in humans.

Toxicology and Applied Pharmacology 2018 August 2 [Link] Garabrant DH, Pastula ST Abstract We analyzed the mesothelioma mortality in cohorts of workers exposed to crocidolite, amosite, and chrysotile to estimate asbestos fiber potency for mesothelioma, using the method of Hodgson and Darnton (2000). We relied on the original 17 cohort studies in their analysis, along […]

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Pre-clinical Models for Malignant Mesothelioma Research: From Chemical-Induced to Patient-Derived Cancer Xenografts.

Frontiers in Genetics 2018 July 4 [Link] Nabavi N, Wei J, Lin D, Collins CC, Gout PW, Wang Y Abstract Malignant mesothelioma (MM) is a rare disease often associated with environmental exposure to asbestos and other erionite fibers. MM has a long latency period prior to manifestation and a poor prognosis. The survival post-diagnosis is […]

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Epidemiological surveillance of mesothelioma mortality in Italy.

Cancer Epidemiology 2018 July 7 [Link] Fazzo L, Minelli G, De Santis M, Bruno C, Zona A, Conti S, Comba P Abstract BACKGROUND: Malignant mesothelioma (MM) is causally linked to asbestos exposure with an estimated etiological fraction of 80% or more. METHODS: Standardized rates of all mesothelioma (C45, ICD-10) and malignant pleural mesothelioma (C45.0, ICD-10) […]

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Malignant mesothelioma diagnosed at a younger age is associated with heavier asbestos exposure.

Carcinogenesis 2018 June 30 [Link] Dragani TA, Colombo F, Pavlisko EN, Roggli VL Abstract Asbestos exposure is the main etiology of malignant mesothelioma, but there are conflicting data on whether the intensity of exposure modulates the development of this disease. This study considered 594 patients with malignant mesothelioma for whom count data on asbestos bodies […]

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Measuring EMPs in the lung what can be measured in the lung: Asbestiform minerals and cleavage fragments.

Toxicology and Applied Pharmacology 2018 June 27 [Link] Roggli VL Abstract Asbestos mineral fibers have been associated with the development of a variety of diseases in humans and experimental animals, including asbestosis, lung cancer, and mesothelioma. Asbestos includes several mineral types divided into two mineral groups, serpentine and amphibole forms. Chrysotile is the serpentine mineral […]

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The asbestos-carbon nanotube analogy: An update.

Toxicology and Applied Pharmacology 2018 June 27 [Link] Kane AB, Hurt RH, Gao H Abstract Nanotechnology is an emerging industry based on commercialization of materials with one or more dimensions of 100 nm or less. Engineered nanomaterials are currently incorporated into thin films, porous materials, liquid suspensions, or filler/matrix nanocomposites with future applications predicted in energy […]

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Cancer incidence in a cohort of asbestos-exposed workers undergoing health surveillance.

International Archives of Occupational and Environmental Health 2018 June 5 [Link] Barbiero F, Zanin T, Pisa FE, Casetta A, Rosolen V, Giangreco M, Negro C, Bovenzi M, Barbone F Abstract OBJECTIVES: To compare a local cohort of 2488 men occupationally exposed to asbestos and enrolled in a public health surveillance program with the 1995-2009 cancer […]

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A review of the cohorts with environmental and occupational mineral fiber exposure.

Archives of environmental and occupational health 2018 April [Link] Metintas S, Ak G, Metintas M Abstract The aim of the study was to examine factors associated with Malignant Mesothelioma (MM) incidence rate of the groups with occupational asbestos and environmental asbestos or erionite exposure in rural area. In this ecological study, a total of 21 […]

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New Perspectives on Diagnosis and Therapy of Malignant Pleural Mesothelioma

Frontiers in Oncology 2018 April [Link] Rossini M, Rizzo P, Bononi I, Clementz A, Ferrari R, Martini F, Tognon MG Abstract Malignant pleural mesothelioma (MPM) is a rare, but severe form of cancer, with an incidence that varies significantly within and among different countries around the world. It develops in about one to two persons […]

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Asbestos Fiber Concentrations in the Lungs of Brake Repair Workers: An Updated Analysis Using Several Regression Methods to Handle Non-Detectable Measurements

Journal of Occupational and Environmental Medicine 2018 March [Epub ahead of print] [Link] Liu Y1, Marsh GM, Roggli VL Abstract OBJECTIVES: To reanalyze an updated database of lung asbestos fiber levels for 21 brake repair workers who died of mesothelioma using robust maximum likelihood-based regression methods to address non-detectable measurements. METHODS: We applied bivariate normal […]

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