MesotheliomaCenter's

Mesothelioma-Line

Curated Journal Articles on Mesothelioma

Category Archives: Causation

Articles dealing with the factors influencing the development of mesothelioma; occupational asbestos exposure is among the most common, but also genetic predisposition, smoking, and other contributing factors.

Pleural mesothelioma and lung cancer: the role of asbestos exposure and genetic variants in selected iron metabolism and inflammation genes.

Journal of Toxicology and Environmental Health 2019 November 22 [Link] Celsi F, Crovella S, Moura RR, Schneider M, Vita F, Finotto L, Zabucchi G, Zacchi P, Borelli V Abstract Two of the major cancerous diseases associated with asbestos exposure are malignant pleural mesothelioma (MPM) and lung cancer (LC). In addition to asbestos exposure, genetic factors […]

Comments Off on Pleural mesothelioma and lung cancer: the role of asbestos exposure and genetic variants in selected iron metabolism and inflammation genes.

[Screening of occupational exposure to asbestos and silica by job-exposure matrix among patients with lung cancer and mesothelioma].

Revue des Maladies Respiratoires 2019 November 11 [Link] Lorentz E, Despreaux T, Quignette A, Chinet T, Descatha A Abstract INTRODUCTION: In the context of underreporting of occupational diseases, the aim was to study the validity of silica and asbestos job-exposure matrices in screening occupational exposure in the field of thoracic oncology. METHODS: Fifty patients hospitalized […]

Comments Off on [Screening of occupational exposure to asbestos and silica by job-exposure matrix among patients with lung cancer and mesothelioma].

Malignant Mesothelioma Among Employees of a Connecticut Factory That Manufactured Friction Materials Using Chrysotile Asbestos: An Update.

Annals of Work Exposures and Health 2019 November 12 [Link] Finkelstein MM, Meisenkothen C Abstract There is an ongoing argument about the potency of chrysotile asbestos to cause malignant mesothelioma. Authors of chrysotile risk assessments have relied upon the results of an epidemiologic study, published in 1984, to state that there were no mesotheliomas found […]

Comments Off on Malignant Mesothelioma Among Employees of a Connecticut Factory That Manufactured Friction Materials Using Chrysotile Asbestos: An Update.

Follow-Up of the Libby, Montana Screening Cohort: A 17-Year Mortality Study.

Journal of Occupational and Environmental Medicine 2019 November 8 [Link] Larson TC, Williamson L, Antao VC Abstract OBJECTIVE: To evaluate mortality patterns among participants in a community-based screening program for asbestos-related disease. METHODS: We calculated standardized mortality ratios (SMRs) and stratified results by exposure group (three occupational exposure groups, household contacts and residents without occupational […]

Comments Off on Follow-Up of the Libby, Montana Screening Cohort: A 17-Year Mortality Study.

The occurrence of asbestos-related diseases among former employees of asbestos processing plants in Poland

Medycyna Pracy 2019 October 23 [Link] Świątkowska B Abstract BACKGROUND: Despite the fact that asbestos is no longer used in production in Poland, there are still new cases of asbestos-related diseases among workers previously exposed to asbestos dust. This situation is related to the specificity of the biological activity of this mineral; the health consequences […]

Comments Off on The occurrence of asbestos-related diseases among former employees of asbestos processing plants in Poland

Modulation of Calretinin Expression in Human Mesothelioma Cells Reveals the Implication of the FAK and Wnt Signaling Pathways in Conferring Chemoresistance towards Cisplatin.

International Journal of Molecular Science 2019 October 29 [Link] Wörthmüller J, Salicio V, Oberson A, Blum W, Schwaller B Abstract Malignant mesothelioma (MM) is an aggressive asbestos-linked neoplasm, characterized by dysregulation of signaling pathways. Due to intrinsic or acquired chemoresistance, MM treatment options remain limited. Calretinin is a Ca2+-binding protein expressed during MM tumorigenesis that […]

Comments Off on Modulation of Calretinin Expression in Human Mesothelioma Cells Reveals the Implication of the FAK and Wnt Signaling Pathways in Conferring Chemoresistance towards Cisplatin.

Mesothelioma mortality in Great Britain: how much longer will dockyards dominate?

Occupational and Environmental Medicine 2019 October 29 [Link] Reynolds CJ, Minelli C, Darnton A, Cullinan P Abstract OBJECTIVES: We aimed to investigate whether there has been a geographic shift in the distribution of mesothelioma deaths in Great Britain given the decline of shipbuilding and progressive exposure regulation. METHODS: We calculated age-adjusted mesothelioma mortality rates and […]

Comments Off on Mesothelioma mortality in Great Britain: how much longer will dockyards dominate?

Approved and emerging treatments of malignant pleural mesothelioma in elderly patients.

Expert Review of Respiratory Medicine 2019 October 9 [Link] Ceresoli GL, Rossi A Abstract Introduction: Malignant pleural mesothelioma (MPM) is a rare neoplasm with asbestos exposure as the dominant etiologic agent. Owing to the long latent period following exposure, MPM is often diagnosed late in life. Despite this, elderly patients are under-represented in clinical trials. […]

Comments Off on Approved and emerging treatments of malignant pleural mesothelioma in elderly patients.

Malignant mesothelioma in construction workers: the Apulia regional mesothelioma register, Southern Italy.

BMC Research Notes 2019 September 30 [Link] Vimercati L, Cavone D, Caputi A, Delfino MC, De Maria L, Ferri GM, Serio G Abstract OBJECTIVE: Asbestos was widely used in construction in both a friable and a compact form until the 1990s, before its use was banned. Today, many of these materials are still in situ […]

Comments Off on Malignant mesothelioma in construction workers: the Apulia regional mesothelioma register, Southern Italy.

Malignant Mesothelioma: Has Anything Changed?

Seminars in Respiratory and Critical Care Medicine 2019 June [Link] Kim RY1, Sterman DH2, Haas AR3 Abstract Malignant pleural mesothelioma is a rare cancer associated with asbestos exposure and portends a dismal prognosis. Its worldwide incidence has been increasing, and treatment options are currently suboptimal and noncurative. However, since the turn of the century, several […]

Comments Off on Malignant Mesothelioma: Has Anything Changed?