MesotheliomaCenter's

Mesothelioma-Line

Curated Journal Articles on Mesothelioma

Category Archives: Causation

Articles dealing with the factors influencing the development of mesothelioma; occupational asbestos exposure is among the most common, but also genetic predisposition, smoking, and other contributing factors.

The significance of non-occupational asbestos exposure in women with mesothelioma.

Respirology Case Reports 2018 November 20 [Link] Tlotleng N, Sidwell Wilson K, Naicker N, Koegelenberg CF, Rees D, Phillips JI Abstract Malignant mesothelioma is a rare and aggressive pleural or peritoneal tumour almost always caused by exposure to asbestos fibres. Exposure to asbestos can cause malignant mesothelioma 30-40 years after exposure. A description of sources of […]

Comments Off on The significance of non-occupational asbestos exposure in women with mesothelioma.

Decrease in Intracellular Perforin Levels and IFN-γ Production in Human CD8+ T Cell Line following Long-Term Exposure to Asbestos Fibers.

Journal of Immunology Research 2018 October 23 [Link] Kumagai-Takei N1, Nishimura Y, Matsuzaki H, Lee S, Yoshitome K, Otsuki T Abstract Although the tumorigenicity of asbestos, which is thought to cause mesothelioma, has been clarified, its effect on antitumor immunity requires further investigation. We previously reported a decrease in the percentage of perforin+ cells of […]

Comments Off on Decrease in Intracellular Perforin Levels and IFN-γ Production in Human CD8+ T Cell Line following Long-Term Exposure to Asbestos Fibers.

The role of fiber type and cumulative exposure in controlling mesothelioma risk.

Toxicology and Applied Pharmacology 2018 October 28 [Link] Langer AM, Nolan RP Abstract The acceptance of primary tumors arising on the serosal surface of body cavities and its association with asbestos exposure was established in 1960. Epidemiological studies followed in an effort to determine if all asbestos fiber types produced the same malignancy and with […]

Comments Off on The role of fiber type and cumulative exposure in controlling mesothelioma risk.

A Subset of Mesotheliomas With Improved Survival Occurring in Carriers of BAP1 and Other Germline Mutations.

Journal of Clinical Oncology 2018 October 30 [Link] Pastorino S, Yoshikawa Y, Pass HI, Emi M, Nasu M, Pagano I, Takinishi Y, Yamamoto R, Minaai M, Hashimoto-Tamaoki T, Ohmuraya M, Goto K, Goparaju C, Sarin KY, Tanji M, Bononi A, Napolitano A, Gaudino G, Hesdorffer M, Yang Abstract PURPOSE: We hypothesized that four criteria could […]

Comments Off on A Subset of Mesotheliomas With Improved Survival Occurring in Carriers of BAP1 and Other Germline Mutations.

Sensitivity to asbestos is increased in patients with mesothelioma and pathogenic germline variants in BAP1 or other DNA repair genes.

Genes, Chromosomes, and Cancer 2018 November [Link] Betti M, Aspesi A, Ferrante D, Sculco M, Righi L, Mirabelli D, Napoli F, Rondón-Lagos M, Casalone E, Vignolo Lutati F, Ogliara P, Bironzo P, Gironi CL, Savoia P, Maffè A, Ungari S, Grosso F, Libener R, Boldorini R, Valiante M, Pasini B, Matullo G, Scagliotti G, Mag […]

Comments Off on Sensitivity to asbestos is increased in patients with mesothelioma and pathogenic germline variants in BAP1 or other DNA repair genes.

Neoantigenic potential of complex chromosomal rearrangements in mesothelioma.

Journal of Thoracic Oncology 2018 October 10 [Link] Mansfield AS, Peikert T, Smadbeck JB, Udell JBM, Garcia-Rivera E, Elsbernd L, Erskine CL, Van Keulen VP, Kosari F, Murphy SJ, Ren H, Serla VV, Schaefer Klein JL, Karagouga G, Harris FR, Sosa C, Johnson SH, Nevala W, Markovic SN, Bungum AO, Edell ES, Dong H, Cheville […]

Comments Off on Neoantigenic potential of complex chromosomal rearrangements in mesothelioma.

Prediagnostic detection of mesothelioma by circulating calretinin and mesothelin – a case-control comparison nested into a prospective cohort of asbestos-exposed workers.

Scientific Reports 2018 September 25 [Link] Johnen G1, Burek K, Raiko I, Wichert K, Pesch B, Weber DG, Lehnert M, Casjens S, Hagemeyer O, Taeger D, Brüning T; MoMar Study Group. Abstract Malignant mesothelioma (MM) is strongly associated with a previous asbestos exposure. To improve timely detection of MM in asbestos workers, better screening tools […]

Comments Off on Prediagnostic detection of mesothelioma by circulating calretinin and mesothelin – a case-control comparison nested into a prospective cohort of asbestos-exposed workers.

Mortality in a cohort of asbestos-exposed workers undergoing health surveillance.

La Medicina del Lavoro 2018 February 6 [Link] Barbiero F, Zanin T, Pisa FE, Casetta A, Rosolen V, Giangreco M, Negro C, Bovenzi M, Barbone F Abstract BACKGROUND: The coastal area of Friuli Venezia Giulia (FVG) region, north-eastern Italy, was characterized by work activities in which asbestos was used until the early 1990s, particularly in […]

Comments Off on Mortality in a cohort of asbestos-exposed workers undergoing health surveillance.

Familial risk of pleural mesothelioma increased drastically in certain occupations: A nationwide prospective cohort study.

European Journal of Cancer 2018 September 6 [Link] Kharazmi E, Chen T, Fallah M, Sundquist K, Sundquist J, Albin M, Weiderpass E, Hemminki K Abstract OBJECTIVE: We aimed to explore the effect of occupation on familial risk of pleural mesothelioma in a nationwide cohort study design. METHOD: The nationwide Swedish Family-Cancer Database includes all Swedes […]

Comments Off on Familial risk of pleural mesothelioma increased drastically in certain occupations: A nationwide prospective cohort study.

Are children more vulnerable to mesothelioma than adults? A comparison of mesothelioma risk among children and adults exposed non-occupationally to blue asbestos at Wittenoom.

Occupational and Outdoor Medicine 2018 August 29 [Link] Reid A, Franklin P, Berry G, Peters S, Sodhi-Berry N, Brims F, Musk AW, de Klerk NH Abstract OBJECTIVES: The presence of asbestos in public buildings is a legacy of past asbestos use in many developed countries. Of particular concern is the amount and current condition in […]

Comments Off on Are children more vulnerable to mesothelioma than adults? A comparison of mesothelioma risk among children and adults exposed non-occupationally to blue asbestos at Wittenoom.