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Curated Journal Articles on Mesothelioma

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Ten-year experience with peritoneal mesothelioma.

Journal of B.U.O.N 2019 January-February [Link] Kyziridis D, Hristakis C, Kalakonas A, Vaikos D, Pallas N, Karamveri C, Kyriakopoulos V, Tentes AA Abstract PURPOSE: Peritoneal mesothelioma is a rare disease that remains confined to the peritoneal surfaces for long. Cytoreductive surgery (CRS) combined with hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) is the most effective treatment and […]

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The Investigation of Lipoxygenases as Therapeutic Targets in Malignant Pleural Mesothelioma.

Pathology Oncology Research 2019 April 2 [Link] Oguh-Olayinka L, Agarwal V, Ranatunge D, Campbell A, Laufer S, Cawkwell L, Lind MJ Abstract Advanced malignant pleural mesothelioma (MPM) has an extremely poor prognosis with limited chemotherapy options, therefore the identification of new therapeutic targets would aid in disease management. Arachidonic acid is metabolised by cyclooxygenase and […]

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Droplet digital PCR as a novel system for the detection of microRNA‑34b/c methylation in circulating DNA in malignant pleural mesothelioma.

International Journal of Oncology 2019 April 1 [Link] Sato H, Soh J, Aoe K, Fujimoto N, Tanaka S, Namba K, Torigoe H, Shien K, Yamamoto H, Tomida S, Tao H, Okabe K, Kishimoto T, Toyooka S Abstract Malignant pleural mesothelioma (MPM) is a rare malignancy arising from the pleura that is difficult to diagnose, contributing […]

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A case from India of pleural malignant mesothelioma probably due to domestic and environmental asbestos exposure: a posthumous report.

BMJ Case Reports 2019 March 31 [Link] Muralidhar V, Raghav P, Das P, Goel A Abstract India is the largest consumer of asbestos in the world. There is no report from India of mesothelioma related to asbestos. The case is a 42-year-old man who died of pleural mesothelioma. He was exposed to asbestos domestically and […]

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Prophylactic Irradiation of Tracts in Patients With Malignant Pleural Mesothelioma: An Open-Label, Multicenter, Phase III Randomized Trial.

Journal of Clinical Oncology 2019 March 28 [Link] Bayman N, Appel W, Ashcroft L, Baldwin DR, Bates A, Darlison L, Edwards JG, Ezhil V, Gilligan D, Hatton M, Jegannathen A, Mansy T, Peake MD, Pemberton L, Rintoul RC, Snee M, Ryder WD, Taylor P, Faivre-Finn C Abstract PURPOSE: Prophylactic irradiation to the chest wall after […]

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Tomotherapy in malignant mesothelioma: a planning study to establish dose constraints.

Strahlentherapie and Onkologie 2019 March 26 [Link] Leitzen C, Wilhelm-Buchstab T, Stumpf S, Heimann M, Koch D, Schmeel C, Simon B, Vornholt S, Garbe S, Röhner F2, Schoroth F, Schild HH, Schüller H, Müdder T Abstract PURPOSE: A planning study was performed for helical tomotherapy treatment. We evaluated the maximum achievable protection of organs at risk […]

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Asbestos fiber identification in liver from cholangiocarcinoma patients living in an asbestos polluted area: a preliminary study.

Tumori 2019 March 27 [Link] Grosso F, Croce A, Libener R, Mariani N, Pastormerlo M, Maconi A, Rinaudo C Abstract PURPOSE:: To assess whether asbestos fibers may be observed in liver tissue of patients with cholangiocarcinoma (CC) with environmental or working asbestos exposure. METHODS:: Detection of fibers was performed directly on histologic sections of liver […]

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Epidermal growth factor receptor (EGFR)-targeted therapies in Mesothelioma.

Expert Opinion on Drug Delivery 2019 March 27 [Link] Chia PL, Scott AM, John T Abstract Malignant mesothelioma (MM) is an aggressive malignancy arising from the mesothelial cells lining the pleura and other serosal membranes. It is associated with an extremely poor prognosis and has limited therapeutic options. Areas covered: Epidermal growth factor receptor (EGFR) […]

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Making cold malignant pleural effusions hot: driving novel immunotherapies.

Oncoimmunology 2019 January 22 [Link] Murthy P, Ekeke CN, Russell KL, Butler SC, Wang Y, Luketich JD, Soloff AC, Dhupar R, Lotze MT Abstract Malignant pleural effusions, arising from either primary mesotheliomas or secondary malignancies, heralds advanced disease and poor prognosis. Current treatments, including therapeutic thoracentesis and tube thoracostomy, are largely palliative. The immunosuppressive environment […]

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Hyperthermic Intrathoracic Chemotherapy (HITHOC) for Pleural Malignancies-Experience from Indian Centers.

Indian Journal of Surgical Oncology 2019 February [Link] Patel MD, Damodaran D, Rangole A, Shaikh S, Shah K, Bagwade R, Bhatt A Abstract Hyperthermic intrathoracic chemotherapy (HITHOC) has been used in addition to radical surgery for primary and secondary pleural malignancies to improve local control, prolong survival, and improve the quality of life. This study was […]

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