Academic Radiology 2017 April 20 [Epub ahead of print] [Link] Pena E, Ojiaku M, Inacio JR, Gupta A, Macdonald DB, Shabana W, Seely JM, Rybicki FJ, Dennie C, Thornhill RE Abstract RATIONALE AND OBJECTIVES: The study aimed to identify a radiomic approach based on CT and or magnetic resonance (MR) features (shape and texture) that […]
Category Archives: Full Archive
Current Opinion in Pulmonary Medicine 2017 April [Epub ahead of print] [Link] Arnold DT, Clive AO Abstract PURPOSE OF REVIEW: Malignant pleural mesothelioma is an aggressive malignancy with a very poor prognosis. The majority of patients require pleural procedures for diagnostic or fluid management purposes. Damage to the pleura during these procedures can lead to […]
Three-dimensional finite-element based deformable image registration for evaluation of pleural cavity irradiation during photodynamic therapy
Medical Physics 2017 April [Epub ahead of print] [Link] Penjweini R, Kim MM, Zhu TC Abstract PURPOSE: Photodynamic therapy (PDT) is used after surgical resection to treat the microscopic disease for malignant pleural mesothelioma and to increase survival rates. As accurate light delivery is imperative to PDT efficacy, the deformation of the pleural volume during […]
Pleurectomy-decortication in malignant pleural mesothelioma: are different surgical techniques associated with different outcomes? Results from a multicentre study
European Journal of Cardio-Throacic Surgery 2017 April [Epub ahead of print] [Link] Marulli G, Breda C, Fontana P, Ratto GB, Leoncini G, Alloisio M, Infante M, Luzzi L, Paladini P, Oliaro A, Ruffini E, Benvenuti MR, Pariscenti G, Spaggiari L, Casiraghi M, Rusca M, Carbognani P, Ampollini L, Facciolo F, Leuzzi G, Mucilli F, Camplese […]
Folic acid phenotype (FAP) is a superior biomarker predicting response to pemetrexed-based chemotherapy in malignant pleural mesothelioma
Oncotarget 2017 March [Epub ahead of print] [Link] Mairinger FD, Vollbrecht C, Flom E, Christoph DC, Schmid KW, Kollmeier J, Popper HH, Mairinger T, Walter RFH Abstract BACKGROUND: Malignant pleural mesothelioma (MPM) is a rare tumor linked to a dismal prognosis. Even the most effective chemotherapeutical regime of pemetrexed combined with cisplatin leads to a […]
Journal of Thoracic Oncology 2017 April [Epub ahead of print] [Link] Bian L, van Gerwen M, Bonassi S, Taioli E; IASLC Mesothelioma Taskforce Abstract While the association between exposure to asbestos and malignant mesothelioma (MM), particularly malignant pleural mesothelioma (MPM) has been well established, the health impact of environmental exposure (EE) to asbestos is less […]
CD44 and its ligand hyaluronan as potential biomarkers in malignant pleural mesothelioma: evidence and perspectives.
Respiratory Research 2017 April [Link] Cortes-Dericks L, Schmid RA Abstract Malignant pleural mesothelioma (MPM) is a rare and highly drug resistant tumor arising from the mesothelial surfaces of the lung pleura. The standard method to confirm MPM is the tedious, time-consuming cytological examination of cancer biopsy. Biomarkers that are detectable in pleural effusion or patient […]
Malignant pleural mesothelioma: single-institution experience of 101 patients over a 15-year period.
Acta Chirugica Belgica 2017 June [Link] Domen A, De Laet C, Vanderbruggen W, Gielis J, Hendriks JM, Lauwers P, Janssens A, Hiddinga B, Van Meerbeeck JP, Van Schil PE Abstract BACKGROUND: Malignant pleural mesothelioma (MPM) is a rare but aggressive neoplasm that typically originates from the mesothelial surfaces of the pleural cavity. Exposure to asbestos […]
Environmental Research 2017 April [Epub ahead of print] [Link] Rapisarda V, Caltabiano R, Musumeci G, Castrogiovanni P, Ferrante M, Ledda C, Lombardo C, Graziano AC, Cardile V, Loreto C Abstract A significantly increased incidence of malignant mesothelioma in Biancavilla (Sicily, Italy) has been ascribed to exposure to fluoro-edenite, a fibrous amphibole extracted from a local […]
A novel BRCA1-associated protein-1 isoform affects response of mesothelioma cells to drugs impairing BRCA1-mediated DNA repair.
Journal of Thoracic Oncology 2017 April [Epub ahead of print] [Link] Parrotta R, Okonska A, Ronner M, Weder W, Stahel R, Penengo L, Felley-Bosco E Abstract INTRODUCTION: BRCA1-associated protein-1, BAP1, is a tumor suppressor involved in multiple cellular processes such as transcriptional regulation, chromatin modification by deubiquitinating histone 2A and DNA repair. BAP1 mutations are […]