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Curated Journal Articles on Mesothelioma

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The full archive of mesothelioma-related journal articles. All articles belong to this category.

Hyaluronic acid enhances cell migration and invasion via the YAP1/TAZ-RHAMM axis in malignant pleural mesothelioma

Oncotarget 2017 September [Link] Shigeeda W Abstract Most malignant mesotheliomas (MPMs) frequently show activated forms of Yes-associated protein 1 (YAP1) and transcriptional co-activator with PDZ-binding motif (TAZ), which transcriptionally regulates the receptor for hyaluronic acid-mediated motility (RHAMM). As RHAMM is involved in cell migration and invasion in various tumors, we speculated that hyaluronic acid (HA) […]

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National Trends in the Epidemiology of Malignant Pleural Mesothelioma: A National Cancer Data Base Study

The Annals of Thoracic Surgery 2017 December [Epub ahead of print] [Link] Saddoughi SA, Abdelsattar ZM, Blackmon SH Abstract BACKGROUND: Malignant pleural mesothelioma (MPM) remains an aggressive malignancy that is difficult to cure. However, the treatment paradigm of MPM has evolved, and the national practice patterns are unknown. This study examined the national trends in […]

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Efficacy of sonographic and biological pleurodesis indicators of malignant pleural effusion (SIMPLE): protocol of a randomised controlled trial

BMJ Open Respiratory Research 2017 November [Link] Psallidas I et.al Abstract INTRODUCTION: Malignant pleural effusion (MPE) is common and currently in UK there are an estimated 50 000 new cases of MPE per year. Talc pleurodesis remains one of the most popular methods for fluid control. The value of thoracic ultrasound (TUS) imaging, before and […]

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Recent Advances in the Diagnosis of Malignant Mesothelioma: Focus on Approach in Challenging Cases and in Limited Tissue and Cytologic Samples

Advances in Anatomic Pathology 2018 January [Link] Monaco S, Mehrad M, Dacic S Abstract Mesothelial proliferations can be diagnostically challenging in small specimens, such as body fluid cytology and small tissue biopsies. A great morphologic challenge for pathologists is the separation of benign reactive mesothelial proliferations from malignant mesotheliomas. Reactive mesothelial proliferations may have histologic […]

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Elevated brain natriuretic peptide (BNP) is an early marker for patients at risk for complications after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS + HIPEC)

Journal of Surgical Oncology 2017 November 28 [Epub ahead of print] [Link] Fisher SB, Rafeeq S, Hess K, Grotz TE, Mansfield P, Royal R, Badgwell B, Fleming J, Fournier K, Mann GN Abstract BACKGROUND: Elevated BNP is associated with adverse cardiac outcomes after noncardiac surgery. We assessed BNP values as markers of perioperative fluid status […]

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Phlebotomy as a preventive measure for crocidolite-induced mesothelioma in male rats

Cancer Science 2017 November 29 [Epub ahead of print] [Link] Ohara Y, Chew SH, Shibata T, Okazaki Y, Yamashita K, Toyokuni S Abstract Malignant mesothelioma (MM) is a rare but socially important neoplasm due to its association with asbestos exposure. While MM is difficult to diagnose at an early stage, there are no particularly effective […]

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Clinical presentation, diagnosis, classification and management of peritoneal mesothelioma: a review

Journal of Gastrointestinal Oncology 2017 October [Link] García-Fadrique A, Mehta A, Mohamed F, Dayal S, Cecil T, Moran BJ Abstract Peritoneal mesothelioma (PM) is an uncommon but a serious, and often, fatal primary peritoneal tumour, with increasing incidence worldwide. Conventional systemic chemotherapy, generally based on experience with pleural mesothelioma, usually has disappointing results considering PM […]

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A Case of the Resected Lymphohistiocytoid Mesothelioma: BAP1 Is a Key of Accurate Diagnosis

Anticancer Research 2017 December [Link] Matsubara T Abstract BACKGROUND: Malignant mesothelioma (MM) is a well-known malignant tumor that occurs in the pleura and is histopathologically classified into three subtypes. Lymphohistiocytoid mesothelioma (LHM) is considered a variant of epithelioid MM, and few cases have been reported. First case of LHM was reported by Henderson et al. […]

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Patterns of care and survival among patients with malignant mesothelioma in the United States

Lung Cancer 2017 October [Epub 2017 August 10] [Link] Enewold L, Sharon E, Thomas A Abstract BACKGROUND: Mesothelioma is a rare malignancy that is associated with poor survival. This study aimed to describe the patterns of care and subsequent survival among malignant mesothelioma patients in the United States, while adjusting for patient demographics and comorbidities. […]

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Diaphragm and lung-preserving surgery with hyperthermic chemotherapy for malignant pleural mesothelioma: A 10-year experience

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