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Journal Articles on Mesothelioma: Cancer Information for Patients and Families

Archive for the 'Deciduoid' Category

Malignant deciduoid mesothelioma (MMD) is a rare variant of epithelioid mesothelioma

Deciduoid news feed.

November 15th, 2008. Ectopic decidual reaction mimicking peritoneal tubercles: a report of three cases

Histology revealed extensive decidualisation. To the best of our knowledge, this is the first report of ectopic decidua mimicking peritoneal tubercles.

March 28th, 2006. Comparative genomic hybridization (cgh) in malignant Deciduoid mesothelioma

Conclusions: Although deciduoid mesotheliomas present numerous genetic changes, we highlighted demonstrated that certain chromosomal regions are preferentially affected. Our findings show that the number of losses is predictive of the clinical outcome for this subtype of mesothelioma subtype.

March 15th, 2006. Deciduoid Peritoneal Mesothelioma in a Dog

Multiple whitish-gray nodules (1–5 mm in diameter) in parietal peritoneum and mesentery were histologically composed of large, proliferating, polygonal or ovoid cells with an abundant eosinophilic, glassy cytoplasm. Immunohistochemical evaluation indicated that the neoplastic cells coexpressed cytokeratin and vimentin with strong and diffuse cytoplasmic staining, and ultrastructural analysis showed long and slender mesothelial-type microvilli; these findings confirmed the mesothelial origin of the tumor.

March 11th, 2006. Deciduosis peritonei–a case report

Conclusion: The differential diagnosis of peritoneal deciduosis included deciduoid mesothelioma, metastatic carcinoma (especially if decidual cells have a vacuolated cytoplasm mimicking signet-ring cells), and metastatic melanoma. Decidual cells showed immunoreactivity for vimentin and progesteron receptors and focal positivity for desmin and smooth muscle actin. The presence of cellular atypia, mitotic activity, and immunoreactivity for cytokeratin 5/6 and calretinin will assist in making the diagnosis of deciduoid mesothelioma. The diagnosis of metastatic carcinoma is assisted by the nuclear features and cytokeratin immunoreactivity. A positive immunostain for S-100 and/or HMB-45 will assist in the diagnosis of metastatic melanoma.

November 25th, 2005. Clear cell mesothelioma of the testis with deciduoid areas–a case report

Awareness of this variant is required to avoid misdiagnosis and treatment as either metastasis from a renal cell carcinoma or as a germ cell tumor. A diagnosis of mesothelioma must be ruled out in elderly patients with epithelial-looking tumor especially if the serum germ cell tumor markers are within normal range.

November 1st, 2005. Immunohistochemical diagnosis of epithelioid mesothelioma: an update

Conclusions: D2-40 and podoplanin are the 2 most recently recognized markers that have been found to be useful in the diagnosis of epithelioid mesotheliomas. Since D2-40 and podoplanin appear to be highly sensitive and specific for epithelioid mesotheliomas, either may be considered for inclusion in the battery of antibodies currently recommended for distinguishing epithelioid mesotheliomas from metastatic carcinomas. However, it should be kept in mind that their utility has not yet been fully determined in routine diagnostic work.

May 1st, 2005. Malignant peritoneal mesothelioma in women: a study of 75 cases with emphasis on their morphologic spectrum and differential diagnosis

The varied morphology of peritoneal malignant mesotheliomas may raise a broad differential diagnosis, but in most cases the resemblance to other tumors is limited. Histochemistry, immunohistochemistry, and electron microscopy may provide important aid, particularly when tissue is limited, but should be needed only occasionally.

March 1st, 2005. Malignant Deciduoid Mesothelioma: A Diagnostic Challenge

The patient died 14 months after the first operation. This observation confirms the poor prognosis of this entity and the importance of the differential diagnosis of pseudotumoral deciduosis.