Archive for the 'Epidemiological' Category
Studies of the causes, distribution, and control of mesothelioma and asbestos diseases in populations.
December 12th, 2007. Environmental exposure to asbestos in the area around Goor has been established as the cause of pleural mesothelioma in women
Conclusion: The environmental pollution to asbestos waste materials in the area around Goor was the main cause of the strongly increased incidence of pleural mesothelioma among women in this area. Taking into account an equal risk among men, the consequences of asbestos exposure in the area around Goor in the next 25 years are likely to result in 2 cases of pleural mesothelioma each year.
December 7th, 2007. The epidemiologic surveillance of malignant mesothelioma in the Lower Iseo Lake area
8 x 100,000, 1977-2005) is the highest never estimate in Italy. The epidemiological surveillance of the mesothelioma appear essential to identify cases unreported and allow the collection of information useful to understand clearly the asbestos exposure effects on health's workers and to estimate the tumour incidence in the population.
December 7th, 2007. Epidemiological surveillance of malignant mesothelioma cases in Italy: incidence and asbestos exposure figures by the Italian mesothelioma registry (ReNaM)
In addition to the conventional sectors (shipbuilding, railways repair and demolition, asbestos-cement production), also textile, building, transport, chemical and glass industries, petroleum and sugar refineries, electricity production and distribution plants are getting involved. Despite the absence of some regions completing the national coverage and the non homogeneity in collecting and coding data, the epidemiological surveillance of malignant mesothelioma carried out by ReNaM is an important tool for the scientific knowledge and the prevention of asbestos-related diseases.
December 7th, 2007. Asbestos exposure in the non-asbestos textile industry: the experience of the Lombardy Mesothelioma Registry
The system devised by the Lombardy Registry had brought to light an occupational hazard in a professional area previously never believed as a source of asbestos exposure. In consideration of the described experience, both environmental and clinical, it seems reasonable to consider the non-asbestos-textile as a new department at risk for asbestos exposure.
December 7th, 2007. Asbestos: a long lasting tragedy. Useful considerations for a historical reconstruction of the most remarkable facts
These legal actions will carry to bankruptcy all the asbestos companies and later to the ban of asbestos. The judicial debates will also uncover "confidential" information useful to better reconstruct the epic, to formulate more dispassionate historical judgments and to allow everyone on answering to more complex questions and more important than how much generally it was previously believed; all this should happen contextualizing the ages in which the scientific acquaintances on the effects of asbestos have been published and disproving prejudgments, able to affect some conclusions of the past.
December 7th, 2007. Renal cell carcinoma with malignant pleural mesothelioma after asbestos exposure: a case report
The incidence is rising in industrialized countries, with the peak expected in the year 2020. However, renal cell carcinoma with malignant pleural mesothelioma is very rare and this is the 2nd case in the Japanese literature.
Posted in Case Study, Causation, Chemotherapy, CT or CAT scan, Diagnosis & Differentiation, Epidemiological, Extrapleural Pneumonectomy (EPP), Full Archive, Occupational Asbestos Exposure, Pleural, Pleural Effusion, Radiation, Surgery, Symptoms & Symptom Management, Treatment, Trimodality Therapy, Type of Assessment:, Type of Mesothelioma: | No Comments »
December 1st, 2007. Soluble mesothelin-related peptides (SMRP) – High stability of a potential tumor marker for mesothelioma
SMRP exhibits excellent stability regarding short-term storage, long-term storage, and repeated freeze/thaw cycles. Scientific studies as well as real life applications that employ SMRP would not be limited by sample stability issues.
November 21st, 2007. Human health effects associated with the commercial use of grunerite asbestos (amosite): Paterson, NJ; Tyler, TX; Uxbridge, UK
In both types of malignancies the concentration of grunerite asbestos (amosite) was very high-over a billion fibers per gram of dried lung tissue. Occupational exposure to airborne concentrations of between 14 and 100 fibers of grunerite asbestos (amosite) per milliliter after 20 year latency causes marked increases in lung cancer, mesothelioma and pulmonary fibrosis (asbestosis).
November 17th, 2007. Mesothelioma: You do not have to work for it
Asbestos exposure induced mesothelioma does not require an occupational type of exposure. Bystander exposures may result in earlier age of disease onset and more aggressive disease progression as described in the following 3 case reports.
November 14th, 2007. An overview of the risk of lung cancer in relation to exposure to asbestos and of taconite miners
There are situations where occupational exposure to chrysotile asbestos has shown no detectable increase in risk of lung cancer. Taconite miners have shown no increased risk of mortality due to lung cancer.
November 9th, 2007. Investigation of exposures to commercial asbestos in northeastern Minnesota iron miners who developed mesothelioma
Of the 15 for whom adequate work histories were available, 14 had identifiable sources of exposure to commercial asbestos in jobs held both inside and outside of the mining industry. The time between employment in these asbestos-exposed occupations and the diagnosis of mesothelioma is consistent with the 20 or more year latency period that has been observed in other studies of this cancer.
November 6th, 2007. Analysis of latency time and its determinants in asbestos related malignant mesothelioma cases of the Italian register
6 years increasing in recent years with a linear trend. Anatomical site, gender and morphology were not relevant for MM latency time whereas a shorter latency period was documented among occupationally exposed subjects (43 years) with respect to environmentally and household exposed ones (48 years).
October 30th, 2007. Mesothelioma in vehicle mechanics: is the risk different for Australians?
Conclusions: Discrepancies between epidemiologic studies and AMR-based calculations cannot be explained by differences in exposure. These discrepancies are most likely attributable to inadequate occupational information and classification in the AMR from 1986 forward and to erroneous assumptions used to derive relative risk estimates for mesothelioma among Australian vehicle mechanics.
October 26th, 2007. Asbestos exposure, legislation and diseases in the Czech Republic
Physicians should focus more on the occupational history of these patients and refer them to the Departments of occupational diseases. Benefits are available for all patients with mesothelioma, in whom industrial hygienists confirm former exposure to asbestos, corresponding to the latency period.
October 24th, 2007. Peritoneal mesothelioma: a review
The incidence has increased in the past 2 decades. Only 20% to 33% of all mesotheliomas arise from the peritoneum itself; the pleura is the most common site of origin.
October 17th, 2007. Cancer mortality and incidence of mesothelioma in a cohort of wives of asbestos workers in Casale Monferrato, Italy
Conclusions: Household exposure, as experienced by these AC workers’ wives, increases risk for pleural MM but not for lung cancer.
October 3rd, 2007. Mesothelioma of the pleura in the Province of Trieste
Conclusions: In the Province of Trieste the mesothelioma epidemic does not show any signs of abatement. Besides marine work, a variety of other occupations appear to be associated with the tumour in this area.
Posted in Causation, Diagnosis & Differentiation, Epidemiological, Full Archive, Occupational Asbestos Exposure, Pleural, Pleurectomy/decortication, Pneumonectomy, Surgery, thoracoscopy, Type of Assessment:, Type of Mesothelioma: | No Comments »
October 2nd, 2007. Genetic susceptibility to malignant mesothelioma and exposure to asbestos: The influence of the familial factor
Conclusions: The evaluation of the published materials supports the hypothesis that – although familial clustering of MM is largely attributable to shared asbestos exposure – the additional contribution of factors dealing with genetic susceptibility may play a role in the etiology of MM.
September 29th, 2007. Histopathological diagnosis of pneumoconiosis
One study, using appropriate methods of scientific investigation to evaluate the effects of such exposure on the health of asbestos mine workers in Brazil was conducted as part of a multicenter study and entitled "Morbidity and Mortality Among Workers Exposed to Asbestos in Mining Activities, 1940-1996". Drawing upon the experience acquired during the course of that study, the objective of the current report was to give an overview of asbestos-related diseases, with a special focus on the difficulties involved in establishing the histopathological diagnosis.
September 27th, 2007. First and subsequent asbestos exposures in relation to mesothelioma and lung cancer mortality
The SMR of mesothelioma was strongly related to time since first exposure. The SMR of lung cancer, but not of mesothelioma, appeared to be related to subsequent exposures.
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