Archive for the 'Epidemiological' Category
Studies of the causes, distribution, and control of mesothelioma and asbestos diseases in populations.
May 30th, 2008. Two cases of asbestosis and one case of rounded atelectasis due to non-occupational asbestos exposure
The three cases indicate that non-neoplastic, long-latency asbestos-related diseases which are usually observed as a consequence of occupational exposures, may rarely develop in subjects living in contaminated geographical sites and buildings. These unusual environmental diseases raise the diagnostic problem of differentiating them from other, more common respiratory illnesses, and impose the duties of patient notification, assessment and follow-up, to assess the possibility of progression of disease and increased neoplastic risk.
May 29th, 2008. Erionite-induced pleural plaques : Exposition to urban pollution in a female Turkish migrant in Germany
Short-term clinical and radiologic control of the patient will be necessary because of the risk of MPM. For epidemiologic considerations discussed referring to current literature, a growing incidence of this type of disease in migrants from high-risk areas must be reckoned with in Germany, even without exposition to asbestos.
May 22nd, 2008. Railways and Asbestos in Japan (1928-1987) -Epidemiology of Pleural Plaques, Malignancies and Pneumoconioses
Two cases of mesothelioma were reported in 1980. Pneumoconioses: Most studies (1928-1975) had relatively low prevalence rates among SL-related workers.
May 22nd, 2008. Trends in suspected and recognized occupational respiratory diseases in Germany between 1970 and 2005.
Conclusions: Although trends in occupational disease may be influenced by several factors, the presented data indicate that prevention has been effective in reducing some of the most frequent occupational respiratory diseases in Germany.
May 14th, 2008. Carcinoid Tumours of the Lung and Definition of the Medico-Legal Term “Lung Cancer” Used in the List of Occupational Disease in Germany – Results of the German Mesothelioma Register
4104) the term "lung cancer" is used without further specification. Thus the following question remains open for discussion: does the term "lung cancer" include carcinoid tumours such as malignant epithelial lung tumours, or is it restricted to the common subtypes such as small cell carcinoma, squamous cell carcinoma, adenocarcinoma, large cell carcinoma with regard to occupational disease and compensation.
May 7th, 2008. Mesothelioma in Russia: systematic review of 3576 published cases from occupational medicine viewpoint
The disease is polyetiologic. To restore social justice in relation to mesothelioma patients, scientists should design an algorithm connecting the disease with occupation, create national cancer register for mesothelioma, study prevalence of the disease in separate regions and in the whole country.
April 29th, 2008. Prediction of mesothelioma and lung cancer in a cohort of asbestos exposed workers
Conclusion: This study provides predictions of asbestos-related mortality even in a selected cohort of exposed subjects, using previous knowledge about exposure-response relationship. The inclusion of individual information in the projection model helps reduce misclassification and improves the results. The method could be extended in other selected cohorts.
April 23rd, 2008. Cancer incidence among Finnish farmers, 1995-2005
Conclusions: The cancer incidence of Finnish farmers was significantly below the national average. The finding that lung cancer risk was low among dairy farmers but increased with a change to another type of farm production gives some support to the hypothesis that endotoxin exposure may decrease cancer risk.
April 18th, 2008. Measurement of trends in incidence of work-related skin and respiratory diseases, UK 1996-2005
Conclusions: Some estimated changes in incidence based on volunteer reporting may be biased by reporting fatigue; therefore apparent downward trends need to be interpreted cautiously. Differences in the population bases of the surveillance schemes and UK health service capacity constraints may also explain differences in trends found here.
April 16th, 2008. Work related mesothelioma: analysis of cases discovered at the Section for Occupational Medicine and Toxicology of Siena University during the years 2000-2007
Thus it is possible to find other malignant and nonmalignant asbestos-related diseases more frequently than mesothelioma. There is an evident risk in rebuilding, so the development of new cases due to these exposures is expected.
April 16th, 2008. Malignant mesothelioma (MM) in women: findings of the Mesothelioma Register of the Friuli Venezia Giulia Region
The study highlights the role played by extra-occupational exposure to asbestos among women and the need for careful investigation into previous asbestos exposure in all females with MM. In order to improve our knowledge of the part played by factors other than occupational exposure to asbestos in triggering the disease, it is crucial to reduce he number of cases with no information or "unknown" exposure to this dangerous substance.
April 16th, 2008. Mortality from pleural and peritoneal cancer in a cohort of asbestos workers, many years after start of the exposure: possible role of fibers clearance]
The risk for pleural cancer, rather than showing an indefinite increase, might reach a plateau when a sufficiently long time has elapsed since exposure. The different trends for pleural and peritoneal cancer might be related to clearance of the asbestos from the workers' lungs.
April 16th, 2008. Exposition to asbestos dust in agricultural environment. Some significant exposure forms documented by the Hospital Unit of Occupational Medicine of Hospital Institute of Cremona
At the moment there aren't full-blown asbestos-linked pathology but these workers are potentially at risk of getting them. So it has an importance both on individual and global level for the rural area near Cremona.
April 16th, 2008. Malignant pleuric mesothelioma in Sicily. Epidemiologic observations during the time 1998-2005
We have examined the epidemiologic data of the period 1988-1997 and 1998-2005 through the consultation of the Mesothelioma Sicilian Register; Mesothelioma Italian Register and of the available documentation in the Health Superior Institute. The study showed that the pleural malign mesothelioma in sicily and in Messina's area is reduced for the elimination of the asbestos and for the low use of asbestos in the sicilian industry.
April 16th, 2008. Health surveillance in workers with a previous exposure to asbestos: a method of retrospective evaluation of exposition
Four cases of pulmonary neoplasm and any case of mesothelioma have been diagnosed. This experience shows as the medical surveillance of a homogeneous group of workers can furnish useful data also to frame previous asbestos exposure in absence of environmental data.
April 16th, 2008. Activity of the Campania Register of Mesothelioma from july 2003 to October 2007
16%), Ship building (7. 5%).
Posted in Causation, Epidemiological, Full Archive, General, Occupational Asbestos Exposure, Pericardial, Peritoneal (Abdominal Mesothelioma), Pleural, Tunica Vaginalis Testis, Type of Assessment:, Type of Mesothelioma: | No Comments »
April 16th, 2008. Case studies on the malignant mesothelioma in Pellezzano (SA
All five patients answered the questionnaire and a team of doctors performed an on-the-spot investigation. The studies verified the existence of two kind of asbestos exposure, professional (Cotton Manufacture, Construction, Foundry) and environmental (cement-asbestos pre-fabricated since 1980 earthquake), that have to be analyzed further.
April 9th, 2008. An evaluation of the risks of lung cancer and mesothelioma from exposure to amphibole cleavage fragments
Lawrence, NY talc does not produce mesotheliomas in animals while amphibole asbestos does. In sum, the weight of evidence fully supports a conclusion that non-asbestiform amphiboles do not increase the risk of lung cancer or mesothelioma.
March 15th, 2008. Medico-legal aspects of mesothelioma.
In criminal law, the current approach of the Supreme Court is to demand evidence of strong causality, with a high logical probability and rational credibility, and beyond reasonable doubt, because criminal liability is personal as established in article 27 of the Italian Constitution. It is worth pointing out that all the levels of evidence indicated above must pass the test of scientific suitability or possibility.
March 14th, 2008. Malignant Mesothelioma Resistance to Apoptosis: Recent Discoveries and their Implication for Effective Therapeutic Strategies
The understanding of the molecular mechanisms responsible of the malignant mesothelioma resistance to apoptosis is now advancing, allowing developing new therapeutic strategies to change the natural history and improve survival of patients. This review gives an overview of the main anti-apoptotic strategies devised by malignant mesothelioma and the therapeutic implication and opportunities for this cancer.
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