Archive for the 'Occupational Asbestos Exposure' Category
A wide variety of companies and industries used, and even continue to use, asbestos. While asbestos has never respected job titles, working in certain occupations and industries may increase your likelihood (and that of your family via contaminated clothing) of having been exposed to asbestos.
August 1st, 2008. Update of Potency Factors for Asbestos-Related Lung Cancer and Mesothelioma
, chrysotile or crocidolite) of an asbestos structure. An analysis is conducted to determine how well different KL and KM definitions are able to reconcile the discrepancies observed herein among values obtained from different environments.
July 25th, 2008. Environmental exposure to Libby asbestos and mesotheliomas
Results: These exposures are considered to be of a low degree of magnitude, but are similar to those in Western Australia's crocidolite mine at Wittenoom Gorge. An epidemic of mesothelioma can likely be expected from this type of asbestos contamination over the next 20 plus years.
July 22nd, 2008. Assessment of biomarkers in asbestos-exposed workers as indicators of cancer risk
Subjects heavily exposed to asbestos [>60(ff/cm(3))xyears] showed also a higher level of angiogenic factors. A combination of angiogenic biomarkers with a specific mesothelioma-biomarker such as SMRPs could be used for close surveillance of workers with a history of asbestos exposure.
June 25th, 2008. Asbestos Fibre Concentrations in the Lungs of Brake Workers: Another Look
Conclusions: Re-analysis of published data does not support the interpretation that, in automotive brake repair workers with malignant mesothelioma, asbestos content is within the normal range. The alternative interpretation that brake mechanics have a greater than background burden of asbestos fibres, attributable to occupational exposure to dusts from friction products manufactured from Canadian chrysotile, appears more credible. This asbestos burden might be associated with an increased risk of asbestos-associated cancers.
June 24th, 2008. Separation and Characterization of Respirable Amphibole Fibers from Libby, Montana
Such harvesting of respirable fractions will allow toxicological studies to be conducted within a controlled laboratory setting, utilizing fiber sizes that may more accurately simulate historical exposure of Libby residents' lungs. Importantly, this work describes a method that allows the use of material enriched in more uniform respirable material than raw Libby 6-mix, making comparisons with other known fiber preparations more valid on a mass basis.
June 24th, 2008. Mesothelioma: a still current occupational cancer
In certain circumstances compensation can be obtained at the Occupational Diseases Found. The renewed interest with regard to this tumour is supported by the improvement of mesothelioma management, the new imaging techniques, the new treatments and the broad diffusion of information related to the risk of developing this tumour following asbestos inhalation.
June 11th, 2008. Pemetrexed plus carboplatin in elderly patients with malignant pleural mesothelioma: combined analysis of two phase II trials
Apart from slightly worse haematological toxicity, there was no significant difference in outcome or toxicity between age groups. The PC regimen is effective and well tolerated in selected elderly patients with MPM.
Posted in Carboplatin, Causation, Chemotherapy, Determining Efficacy, Diagnosis & Differentiation, Epidemiological, Full Archive, Immunohistochemistry or IHC, Occupational Asbestos Exposure, Pemetrexed (Alimta), PET Scan, Pleural, Treatment, Type of Assessment: | No Comments »
June 6th, 2008. Excess of Mesotheliomas after Exposure to Chrysotile in Balangero, Italy
Conclusions: The cluster of 14 mesothelioma cases among workers who were active in the mine and 13 among other people exposed to Balangero chrysotile adds further evidence to the carcinogenicity of tremolite-free chrysotile.
June 6th, 2008. Long-term mortality from pleural and peritoneal cancer after exposure to asbestos: Possible role of asbestos clearance
The risk for pleural cancer, rather than showing an indefinite increase, might reach a plateau when a sufficiently long time has elapsed since exposure. The different trends for pleural and peritoneal cancer might be related to clearance of the asbestos from the workers' lungs.
Posted in Causation, Determining Efficacy, Diagnosis & Differentiation, Epidemiological, Full Archive, Imatinib Mesylate (Gleevec/Glivec), Intraperitoneal Chemotherapy, melphalan, Occupational Asbestos Exposure, Oxaliplatin (Eloxatin), paclitaxel, PET Scan, Pleural, Pleural Catheters, Proton Beam Therapy, Staging, Symptoms & Symptom Management, Treatment, Type of Assessment: | No Comments »
June 4th, 2008. An autopsy case of diffuse pleural thickening presented respiratory impairment and benign asbestos pleurisy
The autopsy disclosed asbestos-related lung diseases. We suspected that diffuse pleural thickening could be a major cause of fatal respiratory impairment in this case.
Posted in Case Study, Causation, CT or CAT scan, Diagnosis & Differentiation, Full Archive, Occupational Asbestos Exposure, Pleural Biopsy, Pleural Effusion, Symptoms & Symptom Management, thoracoscopy, Type of Assessment: | No Comments »
June 4th, 2008. Malignant mesothelioma 2008
Novel therapies including intrapleural chemotherapy, photodynamic therapy and hyperthermic perfusion have also been used with some success. Finally there are several attempts at immunomodulating and targeted treatments, which are in phase I/II trials.
Posted in Causation, Chemotherapy, Determining Efficacy, Diagnosis & Differentiation, Full Archive, General, Immune-based Therapies, New & Novel, Occupational Asbestos Exposure, Photodynamic Therapy (PDT), Radiation, Serum Marker/Blood Test, Survival, SV40, Treatment, Type of Assessment: | No Comments »
May 29th, 2008. Malignant mesothelioma of the tunica vaginalis testis in a petrochemical worker exposed to asbestos
Tunical mesothelioma may simulate metastatic carcinoma at routine histopathological examination. Immunohistochemistry and occupational anamnesis are helpful for the correct diagnosis, which, in turn, is important for prognosis and treatment, and in relation to legal issues when asbestos is involved in the causation of the disease.
Posted in Case Study, Causation, Diagnosis & Differentiation, Epithelioid, Full Archive, Immunohistochemistry or IHC, Occupational Asbestos Exposure, Surgery, Treatment, Tunica Vaginalis Testis, Type of Assessment:, Type of Mesothelioma: | No Comments »
May 22nd, 2008. Railways and Asbestos in Japan (1928-1987) -Epidemiology of Pleural Plaques, Malignancies and Pneumoconioses
Two cases of mesothelioma were reported in 1980. Pneumoconioses: Most studies (1928-1975) had relatively low prevalence rates among SL-related workers.
May 22nd, 2008. Trends in suspected and recognized occupational respiratory diseases in Germany between 1970 and 2005.
Conclusions: Although trends in occupational disease may be influenced by several factors, the presented data indicate that prevention has been effective in reducing some of the most frequent occupational respiratory diseases in Germany.
May 21st, 2008. The defence of chrysotile, 1912-2007
Rather, the inquiries constituted elements in the industry's successful public relations exercise that continues to operate to this day. Even when an increasing number of national bodies have legislated for total bans on asbestos use, a policy with which all the international bodies concerned with public health agree, the Canadian PR apparatus continues to be able to call on physicians and scientists prepared to oppose the consensuses reached by the independent advisors to these bodies.
May 15th, 2008. All cause mortality and incidence of cancer in workers in bauxite mines and alumina refineries
71), which was associated with exposures outside the aluminium industry. This study is the first to examine cancer and mortality amongst workers in bauxite mines and alumina refineries and found little evidence for increased cancer incidence or mortality in these workers.
May 14th, 2008. Carcinoid Tumours of the Lung and Definition of the Medico-Legal Term “Lung Cancer” Used in the List of Occupational Disease in Germany – Results of the German Mesothelioma Register
4104) the term "lung cancer" is used without further specification. Thus the following question remains open for discussion: does the term "lung cancer" include carcinoid tumours such as malignant epithelial lung tumours, or is it restricted to the common subtypes such as small cell carcinoma, squamous cell carcinoma, adenocarcinoma, large cell carcinoma with regard to occupational disease and compensation.
May 7th, 2008. Mesothelioma in Russia: systematic review of 3576 published cases from occupational medicine viewpoint
The disease is polyetiologic. To restore social justice in relation to mesothelioma patients, scientists should design an algorithm connecting the disease with occupation, create national cancer register for mesothelioma, study prevalence of the disease in separate regions and in the whole country.
May 7th, 2008. A Technical Comparison of Evaluating Asbestos Concentration by Phase-Contrast Microscopy (PCM), Scanning Electron Microscopy (SEM), and Analytical Transmission Electron Microscopy (ATEM) as Illustrated From Data Generated From a Case Report
These results further indicate that if causation of an asbestos-induced disease such as mesothelioma is based on asbestos concentration of lung tissue, erroneous conclusions can be made by analyzing tissue only by SEM. Thus, the methodologies that are available to analyze asbestos in lung tissue are extensively discussed here with respect to the type of procedure that should be utilized in various situations.
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