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Journal Articles on Mesothelioma: Cancer Information for Patients and Families

Archive for July, 2007

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July 11th, 2007. Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion

02). Activated c-Src may play a role in survival, metastasis, and invasion of MPM, and targeting c-Src may be an important therapeutic strategy.
Posted in Angiogenesis, Diagnosis & Differentiation, Full Archive, Immunohistochemistry or IHC, Kinase Inhibitors, New & Novel, Treatment, Type of Assessment: | No Comments »

July 11th, 2007. Evaluation of a National Register on Occupational Exposure to Carcinogens: Effectiveness in the Prevention of Occupational Cancer, and Cancer Risks among the Exposed Workers

Conclusions: These results suggest that a national exposure register may stimulate preventive measures at workplaces. Partially based on the results of the present study the Finnish Ministry of Social Affairs and Health continues ASA registration.
Posted in Causation, Epidemiological, Full Archive, General, Occupational Asbestos Exposure, Type of Assessment: | No Comments »

July 6th, 2007. Reduced glucose uptake with markedly increased gastrin releasing peptide, osteopontine & asbestos found in dark black areas of PET Scan of chest wall in patient with mesothelioma

In some patients, the only abnormal blood chemistry detected was abnormally increased Pro-Gastrin Releasing Peptide. This dark black area on the PET Scan image taken parallel to front and back of chest wall (with marked increase in asbestos, Gastrin-Releasing Peptide, & Osteopontine and marked decrease in glucose uptake in the pathological tissue) can be considered a characteristic finding for the diagnosis of mesothelioma.
Posted in Diagnosis & Differentiation, Full Archive, PET Scan, Type of Assessment: | No Comments »

July 6th, 2007. Claudin 4 identifies a wide spectrum of epithelial neoplasms and represents a very useful marker for carcinoma versus mesothelioma diagnosis in pleural and peritoneal biopsies and effusions

Results indicate that CL-4 reacts with the majority of epithelial neoplasms that often metastasize to serous membranes, representing a pancarcinoma marker with extremely high sensitivity and specificity. CL-4 may be considered a primary immunohistochemical reagent to rule out the diagnosis of mesothelioma.
Posted in Diagnosis & Differentiation, Full Archive, Immunohistochemistry or IHC, Type of Assessment: | No Comments »

July 6th, 2007. Evaluation of simian virus-40 as a biological prognostic factor in Egyptian patients with malignant pleural mesothelioma

SV40 and asbestos exposure are common in Egyptian MPM, denoting a possible etiological role and a synergistic effect for both agents. Combined positivity for SV40 and asbestos exposure is an independent prognostic factor in MPM, having a detrimental effect on OS.
Posted in Causation, Diagnosis & Differentiation, Environmental Asbestos Exposure, Epidemiological, Full Archive, Immunohistochemistry or IHC, Occupational Asbestos Exposure, SV40, Survival, Type of Assessment: | No Comments »

July 4th, 2007. Constrictive pericarditis after left extrapleural pneumonectomy and radiotherapy for malignant mesothelioma

Our experience, combined with a review of the available literature, leads us to advise a low level of suspicion and early operation to relieve cardiac constriction. Furthermore, these complications emphasize the importance of trials such as the Mesothelioma and Radical Surgery (MARS) study.
Posted in Extrapleural Pneumonectomy (EPP), Full Archive, Pleural, Radiation, Surgery, Symptoms & Symptom Management, Treatment, Type of Assessment:, Type of Mesothelioma: | No Comments »
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