Deciduoid Peritoneal Mesothelioma in a Dog
Wednesday, March 15th, 2006.
Veterinary Pathology. 2006 Feb;43(2):198-201. [Link]
Morini M, Bettini G, Morandi F, Burdisso R, Marcato PS.
Dipartimento di Sanita Pubblica Veterinaria e Patologia Animale, Servizio di Anatomia Patologica, Universita degli Studi di Bologna, via Tolara di Sopra 50, 40064 Ozzano Emilia, Bologna (Italy). bettini@vet.unibo.it.
Abstract
Deciduoid mesothelioma is a rare variant of epithelial mesothelioma, up to now only described in human pathology, which bears remarkable cytomorphologic resemblance to the endometrium of pregnancy, termed decidua. A case of peritoneal mesothelioma with deciduoid features in a 10-year-old, female dog is reported. Multiple whitish-gray nodules (1–5 mm in diameter) in parietal peritoneum and mesentery were histologically composed of large, proliferating, polygonal or ovoid cells with an abundant eosinophilic, glassy cytoplasm. Immunohistochemical evaluation indicated that the neoplastic cells coexpressed cytokeratin and vimentin with strong and diffuse cytoplasmic staining, and ultrastructural analysis showed long and slender mesothelial-type microvilli; these findings confirmed the mesothelial origin of the tumor.
Keywords: Deciduoid mesothelioma; dog; mesothelioma; peritoneum.
Glossary
- tumor
- an abnormal lump or mass of tissue. Tumors can be benign (not cancerous) or malignant (cancerous).
- mesothelioma
- a tumor derived from mesothelial tissue, such as the peritoneum (lining the abdomen) or pleura (lining the lungs). More on mesothelioma.
- peritoneal
- (pair-uh-tuh-nee-al) the serous membrane that lines the cavity of the abdomen. (More on Peritoneal Mesothelioma.)
