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Journal Articles on Mesothelioma: Cancer Information for Patients and Families

Journal Articles on Mesothelioma: November, 2005

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November 2nd, 2005. Needle-track metastases and prophylactic radiotherapy for mesothelioma

Conclusions: Prompt radiotherapy referral and radiotherapy field selection is important to maximise the effect of radiotherapy given to prevent chest wall tumour growth. There was no tumour growth in areas that were treated with radiotherapy. Further chest interventions outside the radiotherapy field should be followed with further radiotherapy.
Posted in Full Archive, Radiation, Treatment, Type of Assessment: | No Comments »

November 1st, 2005. A Phase I and Pharmacokinetic Study of Paclitaxel Poliglumex (XYOTAX), Investigating Both 3-Weekly and 2-Weekly Schedules

Conclusion: PPX is a water-soluble paclitaxel-polymer conjugate with a prolonged half-life and limited volume of distribution. Dose-limiting toxicities were neutropenia and neuropathy. PPX showed activity in this patient population.
Posted in Determining Efficacy, Full Archive, New & Novel, Treatment, Type of Assessment: | No Comments »

November 1st, 2005. Virally directed fluorescent imaging improves diagnostic sensitivity in the detection of minimal residual disease after potentially curative cytoreductive surgery

Specificity of NV1066 infection to tumor nodules was confirmed by immunohistochemistry and by polymerase chain reaction for viral gene. Virally directed fluorescent imaging, a novel molecular imaging technology, can be used for real-time visualization of minimal residual disease after cytoreductive surgery and can improve the completeness of cure-intended resection.
Posted in Diagnosis & Differentiation, Full Archive, Peritoneal (Abdominal Mesothelioma), Surgery, Treatment, Tumor Debulking, Type of Assessment:, Type of Mesothelioma: | No Comments »

November 1st, 2005. Immunohistochemical diagnosis of epithelioid mesothelioma: an update

Conclusions: D2-40 and podoplanin are the 2 most recently recognized markers that have been found to be useful in the diagnosis of epithelioid mesotheliomas. Since D2-40 and podoplanin appear to be highly sensitive and specific for epithelioid mesotheliomas, either may be considered for inclusion in the battery of antibodies currently recommended for distinguishing epithelioid mesotheliomas from metastatic carcinomas. However, it should be kept in mind that their utility has not yet been fully determined in routine diagnostic work.
Posted in Deciduoid, Diagnosis & Differentiation, Full Archive, Type of Assessment:, Type of Mesothelioma: | No Comments »

November 1st, 2005. Recognition of histopathologic patterns of diffuse malignant mesothelioma in differential diagnosis of pleural biopsies

Conclusion: Pathologists should be aware of the varied histologic patterns of diffuse malignant mesothelioma when evaluating pleural biopsies.
Posted in Biphasic or Mixed, Diagnosis & Differentiation, Epithelioid, Full Archive, Pleural Biopsy, Sarcomatoid, Type of Assessment:, Type of Mesothelioma: | No Comments »

November 1st, 2005. Review and update of uncommon primary pleural tumors: a practical approach to diagnosis

Conclusions: Uncommon primary pleural neoplasms may mimic each other, as well as mimic metastatic cancers to the pleura and diffuse malignant mesothelioma. Correct diagnosis is important because of different prognosis and treatment implications for the various neoplasms.
Posted in Diagnosis & Differentiation, Full Archive, Pleural, Symptoms & Symptom Management, Type of Assessment:, Type of Mesothelioma: | No Comments »

November 1st, 2005. Differential diagnosis of benign and malignant mesothelial proliferations on pleural biopsies

Conclusions: Various histologic clues favor a benign over a malignant mesothelial proliferation and vice versa. Invasion is the most reliable criterion for determining that a mesothelial proliferation is malignant. When there is any doubt that a pleural biopsy represents a malignancy, we recommend a diagnosis of atypical mesothelial proliferation.
Posted in Benign, Diagnosis & Differentiation, Full Archive, Pleural, Pleural Biopsy, Type of Assessment:, Type of Mesothelioma: | No Comments »

November 1st, 2005. In-vitro anti-tumor activity studies of bridged and unbridged benzyl-substituted titanocenes

Titanocene Y is most effective on pleura mesothelioma, and uterine and renal cell cancer, where the IC50 values are comparable or significantly better than for cisplatin. In particular, in the case of renal cell cancer and pleura mesothelioma there is an obvious lack of chemotherapeutic reagents, which might be filled by Titanocene Y, where a very promising cytotoxic effect in comparison with cisplatin could be shown.
Posted in Full Archive, New & Novel, Pleural, Treatment, Type of Assessment:, Type of Mesothelioma: | No Comments »
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