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Curated Journal Articles on Mesothelioma

The expected burden of mesothelioma mortality in Great Britain from 2002 to 2050

British Journal of Cancer. (2005) 92, 587-593. doi:10.1038/sj.bjc.6602307 Published online 25 January 2005. [Link]

J T Hodgson1, D M McElvenny1, A J Darnton1, M J Price1 and J Peto2,3

1Epidemiology and Medical Statistics Unit, Health and Safety Executive, Magdalen House, Trinity Road, Bootle, Merseyside L20 3QZ, UK

2Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK

3Epidemiology Section, Institute of Cancer Research, 15 Cotswold Road, Belmont, Sutton, Surrey SM2 5NG, UK

Abstract

The British mesothelioma register contains all deaths from 1968 to 2001 where mesothelioma was mentioned on the death certificate. These data were used to predict the future burden of mesothelioma mortality in Great Britain. Poisson regression analysis was used to model male mesothelioma deaths from 1968 to 2001 as a function of the rise and fall of asbestos exposure during the 20th century, and hence to predict numbers of male deaths in the years 2002-2050. The annual number of mesothelioma deaths in Great Britain has risen increasingly rapidly from 153 deaths in 1968 to 1848 in 2001 and, using our preferred model, is predicted to peak at around 1950 to 2450 deaths per year between 2011 and 2015. Following this peak, the number of deaths is expected to decline rapidly. The eventual death rate will depend on the background level and any residual asbestos exposure. Between 1968 and 2050, there will have been approximately 90,000 deaths from mesothelioma in Great Britain, 65,000 of which will occur after 2001.

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